department of pharmacology


Department News Archive



Updated website

Welcome to the relaunch of the Pharmacology web site! If your browser is Internet Explorer, please use IE7 or above for the best experience. Report any problems to Barry Lukoff.
Posted On 11/8/2009 - Archived On 12/8/2009

Ruth Keri speaks at the next Science Cafe

Due to a fire at Great Lakes Brewery, Ruth Keri's Science Cafe discussion is postponedMore Info


Posted On 11/5/2009 - Archived On 11/9/2009

PHRM 432 now taught by Paul Park

PHRM 432 - Current topics in vision research is now covering a broad range of current topics in vision research.  For more information contact paul.park@case.edu or see the course catalogue online. 
Posted On 10/22/2009 - Archived On 11/21/2009

Marjorie Montanez-Wiscovich, Ph.D.

Congratulations to Marjorie Montanez-Wiscovich who successfully defended her dissertation entitled Discerning the role of LMO4 as a global modulator of G2/M cell cycle progression and centrosome cycle in breast cancer cells.  We wish her the best of luck as she continues her studies with her MD next on the list! 
Posted On 10/22/2009 - Archived On 11/21/2009

Proteomics Course Syllabus (PHRM 555)

The course will be offered for graduate students in the coming spring semester. The Syllabus can be downloaded here.
Posted On 9/14/2009 - Archived On 12/31/2009

Congratulations!

Reema Wahdan-Alaswad recently was granted a National Reserach Service Award through the NIH.  This three year grant will support her studies on mTOR and BMP in prostate cancer.  Good job, Reema! 
Posted On 9/11/2009 - Archived On 10/11/2009

2009 Retreat

The annual Retreat at Geneva on the Lake is on November 19th and 20th
Geneva on the Lake Retreat Information
Posted On 9/1/2009 - Archived On 11/20/2009

Molecular Cell article!

Congratulations to You-Wei Zhang and his recently published article "The F Box Protein Fbx6 Regulates Chk1 Stability and Cellular Sensitivity to Replication Stress" in Molecular Cell.  This study helps understand tumor cell resistance in certain anticancer drugs and is Dr. Zhang's first published paper here in the Department of Pharmacology. 


Posted On 8/17/2009 - Archived On 9/16/2009

Summer Undergraduate Students complete their research

SurpThe final poster session for the Summer Undergraduate Research Program (SURP) showed the cumulative efforts of the departments 8 student researchers.  With topics ranging from anti-obesity activities of palmitoleate to zebra fish models, the students presented some interesting findings.  We wish them all on in their continued studies. 
Posted On 8/10/2009 - Archived On 9/9/2009

In memoriam...

Mona Sternlicht, long-time member of the Pharmacology Community has died.  Mona's quiet confidence was the stabilizing force of the Sternlicht laboratory, and her genteel nature was an inspiration to all of us.  Visitation and Service Information.
Posted On 8/6/2009 - Archived On 9/5/2009

A successful defense!

Congratulations to Jose Gomez who rivited the crowd with his defense entitled "Development of Cell Pentrating Bax Inhibiting Peptides".  Jose has been an intrinsic member of the department and will be greatly missed!  Jose Gomez
Posted On 8/6/2009 - Archived On 9/5/2009

A new leadership role!

To recognize Dr. Amy Wilson-Delfosse's contribution to the School of Medicine, Dr. Daniel Ornt and Dean Pam Davis appointed her as the Assistant Dean, for Basic Science Education.  Dr. Wilson-Defosse is an excellent representative from the Department of Pharmacology in both the School of Medicine curriculum, and coursework.  Congratulations, Amy.
Posted On 7/10/2009 - Archived On 8/9/2009

2,405 citations and counting...

Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor is making headlines...or rather, footnotes.  It is currently ranked as the 5th most cited article in Biology and BioChemistry.  This paper was originally published by our very own chair, Dr. Palczewski in the August 4, 2000 issue of Science.  The heavy citations represent the groundbreaking work that Dr. Palczewski has accomplished in his career and we congratulate him on having such an influential publication. 
Posted On 7/9/2009 - Archived On 8/8/2009

Breakthrough by Bing Cheng Wang!

Not only was it featured in Cancer Cell, but Dr. BC Wang's recent work with EphA2 was written about enthusiastically in the Cleveland Plain Dealer LINK.  His paper "EphA2 Mediates Ligand-Dependent Inhibition and Ligand-Independent Promotion of Cell Migration and Invasion via a Reciprocal Regulatory Loop with Akt" discusses brain tumor progression and it's relationship to the codependency of ephrin-A1 and EphA2. More...


Posted On 7/7/2009 - Archived On 8/6/2009

Fighting breast cancer - Steve Sizemore receives a DoD Postdoctoral Fellowship

FoxC1As part of the 2008 Breast Cancer Research Program, Steve Sizemore was recently awarded a Postdoctoral Fellowship award for 3 years.  The title of his proposal was "FoxC1 in Basal-Type Breast Cancer".
Posted On 6/17/2009 - Archived On 7/17/2009

Research ShowCASE Award Winners!

Emhonta Johnson (Keri Lab) was one of four recipients of a post-doctoral research award for his outstanding poster presentation. The title of his poster was "ErbB2 activation of Rac1/Cdc42 requires p120ctn for induction of tumor cell migration/invasion".

Hany Sobhi (Hoppel Lab) also won a post-doctoral research award.  The title of his poster was titled “Synthesis and Characterization of Lipophilic Coenzyme A, Thioester Derivatives from Nonstandard Medium Chain Fatty Acids”

Reema Wahdan-Alaswad (Danielpour Lab) won 3rd place on her poster presentation.  The title of her poster was “Deregulation of BMP Signaling in Prostate Cancer”
Posted On 4/30/2009 - Archived On 6/30/2009

Dr. Taylor joins the faculty

TaylorDr. Taylor will join the faculty as an Assistant Professor in August. Derek Taylor received his Ph.D. from the University of California, San Diego in 2003 where he was trained in molecular and structural virology in Dr. John (Jack) Johnson's laboratory. For his thesis work, Derek worked on non-enveloped RNA viruses as model systems for viral assembly, maturation, and infection.  The work concentrated specifically on characterizing a pH-dependent, maturational cleavage event, and in determining the atomic structure, using X-ray crystallography, of various viral capsids within the tetravirus family. In 2004, Dr. Taylor began an HHMI post-doctoral fellowship at the Wadsworth Center under the tutelage of Dr. Joachim Frank (now at Columbia University). During the fellowship, Derek used cryo-electron microscopy (cryo-EM) and single particle image reconstruction to visualize eukaryotic ribosomes, stalled at various physiological stages, at sub-nanometer resolution.  In 2008, Derek spent a year with Dr. Tom Cech at the University of Colorado at Boulder working on telomeric complex structure and assembly, which he continues to investigate.
Posted On 4/30/2009 - Archived On 6/30/2009

Dr. Moiseenkova-Bell joins the faculty

Dr. BellDr. Moiseenkova-Bell will join the faculty at Case in the summer of 2009 as Assistant Professor of Pharmacology.  Dr. Moiseenkova-Bell graduate and postdoctoral training have been in membrane protein structure-functional analysis, with an emphasis on TRP (transient receptor potential) channels that play an important role in signal transduction pathways for pain and temperature sensation. She received her Ph.D. from the University of Texas Medical Branch at Galveston in 2004, where she worked in Dr. Burgess Christensen’s laboratory concentrating on the structural and functional analysis of temperature receptors in reptiles and mammals. During her training, she succeeded in the overexpression and purification of the TRP channels using the yeast strain Saccharomyces cerevisiae and showed that this method can produce pure TRPV1 channel suitable for structural work.  That same year, she joined Dr. Theodore Wensel’s laboratory at Baylor College of Medicine, where she continued her work on TRP channels structure determination and solved the first three-dimensional structure of the TRPV1 channel using cryo-electron microscopy and single particles reconstruction. Dr. Moiseenkova-Bell published research papers in journals such as PNAS, Journal of General Physiology, American Journal of Physiology, Biochemical and  Biophysical Research Communications.
Posted On 4/29/2009 - Archived On 6/29/2009

The Newest Board Member

Dr. Amy Wilson-Delfosse is the newest board member in the International Association of Medical Science Educators (IAMSE).  This is a three year term after Dr. Wilson-Delfosse's active involvement in the membership committee.  The IAMSE is founded on the guiding principle to contribute to the efforts of advancing medical education through faculty development and ensuring that the teaching and learning of medicine continues to be firmly grounded in the sciences.
Posted On 4/21/2009 - Archived On 5/21/2009

Outstanding Mentor in Our Midst!

Congratulations to Dr. John Mieyal who is the inaugural recipient of the Inamori Award for Excellence in Mentoring to be presented at this year's Reserach ShowCASE on April 16th at 3:00pm.  Dr. Mieyal was nominated for this award by Dr. Suparna Qanungo who submitted an essay describing Dr. Mieyal's compassionate, consistent and challenging mentoring style.  An outside reviewer judged this essay and Dr. Mieyal's amazing mentoring qualities to be worthy of recognition.  The Inamori International Center for Ethics and Excellence is committed to promoting ethical leadership and is pleased to recognize the positive impact that Dr. Mieyal has on his trainees.  The Department of Pharmacology has long recognized and appreciated Dr. Mieyal's role as a leader and mentor and joins in celebration for this well-deserved recognition!
Posted On 4/15/2009 - Archived On 5/15/2009

Cancer Progression and Metastasis

Congratulations to Melissa Shelton (Keri lab) who was recently awarded a 3 year post-doctoral fellowship by Department of Defense, Breast Cancer Research Program.  Her grant proposal focuses on cancer progression and metastasis
Posted On 3/26/2009 - Archived On 4/25/2009

Breast Cancer Chemoprevention

Congratulations to Nirmala Krishnamurthy (postdoctoral fellow in the laboratory of Dr. Monica Montano) who was just awarded a Department of Defense Postdoctoral Fellowship. Her grant proposal was scored in the outstanding range and will fund her project on breast cancer chemoprevention.
Posted On 3/25/2009 - Archived On 4/25/2009

2009 Sternlicht Memorial Lecture - Horwich

Dr. Arthur Horwich graciously presented for the 2009 Sternlicht Memorial Lectureship in memory of Robert and Hi Sternlicht.  His talk was entitled "Chaperone machines and involvement in a form of ALS". For more information about our special lectureships: http://pharm/calendar/special.aspx
Posted On 3/23/2009 - Archived On 4/22/2009

Dr. Bonomo elected to Association of American Physicians

Dr. Robert Bonomo (http://pharm/department/faculty/secondary/bonomo.aspx), a secondary faculty member in Pharmacology, was recently elected into the Association of American Physicians (http://aap-online.org/).  Annually, 60 individuals are nominated to join, after making significant contributions to the advancement of scientific and practical medicine.  This recognition is an honor and gives members further opportunity to share scientific goals and discoveries.  
Posted On 3/17/2009 - Archived On 4/16/2009

Irina Pikuleva receives the Jules & Doris Stein RPB Professorship Award

Dr. Irina Pikulava, a secondary faculty member in Pharmacology, was the only Research to Prevent Blindness Stein awardee in the United States this year.  This $650,000 grant was established to attract exceptionally talented basic scientists to devote their career to eye research.
Posted On 3/10/2009 - Archived On 4/9/2009

Xiaoxue Zhang Defense

The Department would like to congratulate Xiaoxue Zhang on successfully defending her thesis: 1,25-Dihydroxyvitamin D3-Induced Genes in Osteoblasts: Uncovering New Functions for Meningioma 1 and Semaphorin 3B in Skeletal Physiology.  Xiaoxue has great things ahead of her!
Posted On 2/19/2009 - Archived On 3/21/2009

Greg Tochtrop - A Glennan Fellow

We congratulate Greg Tochtrop, Assistant Professor of Chemistry and a secondary faculty member in Pharmacology on being recently awarded the Glennan Fellowship. This award reflects Dr. Tochtrop's exceptional promise and balance in both teaching and scholarship. This is an honor and a credit to his role in the development of a chemical biology curriculum at CWRU. News Article
Posted On 2/17/2009 - Archived On 3/17/2009

2008 Holiday Party

2008HolidayThe Department of Pharmacology enjoyed a festive holiday party at the George S. Dively Center. Thanks to Drs. Ruth Siegel and Chris Dealwis for organizing this celebration. View pictures here …
Posted On 12/16/2008 - Archived On 2/15/2009

2008 Retreat Photos

Retreat photos are now available here Awards
Posted On 12/8/2008 - Archived On 2/7/2009

Mt. Sinai Scholar in our Midst

Congratulations to Dr. John Feng who has just been named as a Mt. Sinai Scholar! This is a very competitive award provided by the Mt. Sinai Foundation for newly recruited basic science faculty.
Posted On 10/2/2008 - Archived On 11/20/2008

Spotlight Series Prize Award

Congratulations to Dr. Ruth Keri who has been awarded the 2008 keriMather Spotlight Series Prize for Women's Scholarship. Dr. Keri was among eight women scholars who received their awards from President Snyder at a special luncheon in their honor on September 26th. Dr. Keri is an expert in the field of molecular endocrinology and uses genetically manipulated animal models to study molecular mechanisms of reproductive endocrinology.
Posted On 9/26/2008 - Archived On 10/30/2008

K08 Awarded to Maeda!

AkikoMaeda

Congratulations to Dr. Akiko Maeda (Palczewski lab) who has just been awarded a K08 award to fund her research for the next 5 years!!! Dr. Maeda is studying retinal degenerative diseases and working to develop models that will facilitate the evaluation of the safety and efficacy of drug candidates designed to combat retinal disease in humans.
Posted On 8/26/2008 - Archived On 11/25/2008

A new Ph.D.!

We wish Yan Qu the best.  She successfully defended her dissertation "Regulation of Multiple Membrane Trafficking Pathways Stimulated by P2X7 Receptor Activation in Inflammatory Macrophages."  She is leaving Dr. George Dubyak's lab to continue her research as a PostDoctoral Fellow.
Posted On 8/18/2008 - Archived On 9/17/2008

A Successful Dissertation!

Melissa Shelton had a well defended dissertation entitled "Glutaredoxin-Regulated Nuclear Factor-κβ (NFκβ) Signaling in Retinal Müller Glial Cells Treated with High Glucose, a Model of Diabetic Retinopahty." Melissa leaves with not only her PhD but many memories in the Department of Pharmacology!
Posted On 8/5/2008 - Archived On 9/4/2008

Off to bigger and better things...

VivianVivian Gama will be leaving our department after successfully defending her dissertation "Characterization and Regulation of the Anti-apoptotic Protein Ku70 - Implications for Bax-mediated Apoptosis." Her contributions to the department have been immeasurable and we wish her the best in her scientific career. 
Posted On 8/4/2008 - Archived On 9/3/2008

Good Luck!

Hui Wang successfully defeated his defense entitled "The roles of a LIM domain protein, Hic-5 / ARA55, in TGF-β signaling in prostate cancer cells."  We wish him the best as he continues his research in Biostatistics!


Posted On 7/31/2008 - Archived On 8/30/2008

SURP Comes to an End...

At the final poster presentations, 8 summer researchers presented their findings and results.  The students all did a great job and hopefully learned a lot over the last 10 weeks!


Posted On 7/30/2008 - Archived On 8/29/2008

Nature Neuroscience

Don't miss Dr. John Feng's recent article in Nature Neuroscience!

Nature Neuroscience Article


Posted On 7/25/2008 - Archived On 8/24/2008

In the Plain Dealer!

Dr. Kris Palczewski was recently featured in the Cleveland Plain Dealer.  The article is titled "Case Western Reserve's new medical researchers pump millions into Northeast Ohio economy" More Info


Posted On 7/22/2008 - Archived On 8/21/2008

Congratulations!

Smitha Sripathy successfully defended her dissertation, "Mechanisms of Transcriptional Regulation: Gene Repression by KRAB Zinc Finger Proteins and Gene Induction by Estrogen Receptor Beta" on July 14, 2008. We wish her the best in her future Postdoctoral career!
Posted On 7/16/2008 - Archived On 8/18/2008


Dr. Youwei Zhang Joins Pharmacology Faculty

The Department of Pharmacology is pleased to welcome Dr. Youwei Zhang to its faculty! Dr. Zhang is an expert in the field of cell cycle and has published numerous articles on replication checkpoint. Read more about Dr. Zhang and his research.


Posted On 7/15/2008 - Archived On 2/15/2009

Keri Lab Challenge

It was the best of times, it was the worst of times and in the end, the Keri Lab dominated their challenge…... Until next time, that is!


Posted On 6/12/2008 - Archived On 7/12/2008

von Lintig Lab Arrives


The Department of Pharmacology is pleased to welcome Dr. Johannes von Lintig and his lab members, Sylvia Hoff (Research Scholar) and Susanne Hessel (Postdoctoral Fellow)!


Posted On 5/7/2008 - Archived On 7/6/2008

Park Joins Opthalmology Faculty

Congratulations to Dr. Paul Park, a postdoctoral fellow in the Palczewski lab, who has accepted a faculty position in the Department of Opthalmology and Visual Sciences at Case. Paul will begin his tenure track position as an assistant professor July 1 and will continue to pursue his research interests aimed at understanding the signaling mechanism in phototransduction and other G protein-coupled receptor-mediated systems. We wish Paul the best of luck as he pursues his independent career!


Posted On 5/5/2008 - Archived On 6/4/2008

Deans Scientific Research Symposium, 4/30/08

Sponsored by
Dean Pamela B. Davis, M.D., Ph.D.
and the Department of Pharmacology

Download the Symposium Program

Video from Symposium


Posted On 4/24/2008 - Archived On 5/24/2008

Research ShowCASE winners!

Congratulations to our graduate students Vivian Gama and Marjorie Montanez-Wiscovich whose posters were recognized at the 2008 Research ShowCASE.  Vivian received one of only ten Grand Prizes awarded for her poster entitled "Hdm2 is a ubiquitin ligase for the anti-apoptotic protein Ku70",  and Marjorie received an honorable mention for her poster entitled "LMO4 is essential for ErbB2-mediated breast cancer cell proliferation and cell cycle progression."  


Posted On 4/22/2008 - Archived On 5/22/2008

Pharmacology Wins First Place!

A group of students, post-docs, and faculty dominated the field of 16 teams at the First Annual Philanthropy Dodgeball Tournament held on April 13th. The tournament was held to support the activities of the American Red Cross. By going undefeated, Team Pharmacology lived up to their creed -If you ain`t first, you`re last!


Posted On 4/17/2008 - Archived On 5/17/2008

Alumni receives Award

Tehnaz Parakh, a recent MTTP graduate currently in her Med School rotations, has been nominated and will receive, the Noether Memorial Fund Award for excellence in theraputics during the Graduation Award Ceremony.  

Congratulations Tehnaz!'


Posted On 4/8/2008 - Archived On 5/8/2008

NIH funding!

Tonibelle Gatbonton was just awarded a Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows.  Good job, Tonibelle!


Posted On 3/21/2008 - Archived On 4/20/2008

Well defended!

Congratulations to Tim Miller for successfully defending his disertation "FXYD5 modulates Na, K-ATPase activity and is increased in cystic fibrosis airway epithelia."  Tim Miller is leaving Pam Davis's lab and is going to continue his research in the Cleveland area.  We wish him the best!
Posted On 3/21/2008 - Archived On 4/20/2008

ASPET 's recent elections:

  We would like to congratulate Dr. Amy Wilson-Delfosse on her recently elected position as the Secretary-Treasurer-elect of the ASPET Division for Pharmacology Education. This is an honor for Dr. Wilson-Delfosse and is an excellent example of her engagement and dedication to education in the pharmacological sciences!
Posted On 2/27/2008 - Archived On 3/28/2008

Congratulations!

  Krisztina Papp-Wallace successfully defended her dissertation entitled "Studies on the Virulence Properties and Regulation of the CorA Magnesium Channel" on Wednesday, February 20th.  She's now moving from Dr. Mike Maguire's lab to Dr. Robert Bonomo's lab for her Postdoctoral position. 
Posted On 2/27/2008 - Archived On 3/28/2008

Alpha Omega Alpha Honor Medical Society

Congratulations to Tehnaz Parakh (Ph.D. Pharmacology 2006) who has been elected to the Alpha Omega Alpha Honor Medical Society. Election into the society is highly competitive and is reserved for the most accomplished of medical students.


Posted On 1/4/2008 - Archived On 2/3/2008

Holiday Party

Pictures from the holiday party at Shooters on the Water.


Posted On 12/18/2007 - Archived On 1/20/2008

Department of Pharmacology on the Move!

The Department of Pharmacology celebrates the opening of its newly renovated space and also its entry into the top 10 pharmacology departments in the nation!

Open House


Posted On 11/30/2007 - Archived On 3/30/2008

Congratulations!

 

Payal Gandhi successfully defended her dissertation entitled "Characterization of the Parkinson's disease assocated protein, leucine-rich repeat kinase 2 (LRRK2), as a Ras-related GTPase" on 11/16.  We wish Payal the best in her continued research!


Posted On 11/19/2007 - Archived On 12/19/2007

Retreat


Pharmacology Retreat pictures are now available on-line here


Posted On 11/13/2007 - Archived On 12/13/2007

Dr. Andreas Engel

 

The Departmenty of Pharmacology welcomes Dr. Andreas Engel to come speak on the topic of "Electron and Atomic Force Microscopes: Tools for cellular Nanoanalytics" in BRB105 on Thursday, November 15th.


Posted On 11/7/2007 - Archived On 11/16/2007

Dr. Johannes von Lintig joins Pharmacology

 

Dr. von Lintig will join the faculty at Case in spring 2008 as an Assistant Professor of Pharmacology. Read more about Dr. Lintig and his research.


Posted On 11/5/2007 - Archived On 1/31/2008

Dr. John Feng joins Pharmacology


Dr. Feng will join the faculty at Case in the fall of 2007 as Assistant Professor of Pharmacology. Read more about Dr. Feng and his research.


Posted On 10/15/2007 - Archived On 11/14/2007

Palczewski Honored by National Eye Institute

 

Krzysztof Palczewski, Ph.D., John H. Hord Professor and Chair of the Department of Pharmacology has been honored by the National Eye Institute of the National Institutes of Health by being selected as the 2007 Sayer Vision Research Lecture and Award winner.


Posted On 9/29/2007 - Archived On 10/29/2007

Nathan S. Greenfield Family Lecture

 

The Department of Pharmacology is pleased to announce this year's Nathan S. Greenfield Family Lecture. Dr. Dino Moras, Director of Research, CNRS, Strasbourg, France, and Head, Structural Biology Laboratory, Illkirch,France will be speaking on " Nuclear Hormone Receptors: Structural basis for two functional features" on September 25, at 4pm in the Wolstein Auditorium.

 


Posted On 9/14/2007 - Archived On 10/14/2007

Papp-Wallace on Cover!









Congratulations to Krisztina Papp-Wallace of the Maguire laboratory for having her recent review featured on the cover of Molecular Membrane Biology!!!
Read Krisztina's manuscript.






Posted On 9/7/2007 - Archived On 10/7/2007

ACS Fellowship:

Congratulations to Tonibelle Gatbonton who received a Joseph S. Silber Fellowship from the American Cancer Society!
Posted On 8/27/2007 - Archived On 9/26/2007

Dr. Chris Dealwis joins Pharmacology



Dr. Dealwis will join the faculty at Case in the fall of 2007 as Associate Professor of Pharmacology. Read more about Dr. Dealwis and his research.


Posted On 8/6/2007 - Archived On 9/5/2007

Annual Pharmacology Research Symposium

retreat 2007



The 2007 annual Department of Pharmacology Retreat will be held from October 25 to 26 at the Lodge at Geneva State Park. Click here for more information and to register.


Posted On 8/6/2007 - Archived On 9/26/2007

Dr. Shasta Sabo joins Pharmacology


Dr. Sabo will join the faculty at Case in the fall of 2007 as Assistant Professor of Pharmacology. Read more about Dr. Sabo and her research.


Posted On 8/5/2007 - Archived On 8/30/2007

Montano Lab in the news

The Department of Pharmacology was a feature story for WKYC's news story, "Case Medical School encouraging young researchers and future doctors".  The Montano Lab participates in a program that selects local students with an interest in research.  Click here for video


Posted On 8/2/2007 - Archived On 9/1/2007

Pharmacology Backup System is here!


Pharmacology Backup System is launched. Department Members who are in need of a backup tool can register to use this service.
Posted On 7/31/2007 - Archived On 12/30/2007

He did it!

Congratulations to Reggie Gray who successfully defended his dissertation entitled "Regulation of Interferon ?? Induction and Dendritic Cell Function by CpG Oligodeoxynucleotides".  Reggie continues and will be heading off to Virginia Tech to complete his MD.  We wish Reggie all the best in his continued research!


Posted On 7/20/2007 - Archived On 8/19/2007

Well defended!

Congratulations go to Jonathan Mosley who successfully defended
his dissertation entitled "The analysis and utilization of global gene expression data for the study and treatment of breast cancer."
Jonathan defended on June 27th and will now continue finishing his MD/Ph.D. in the School of Medicine.


Posted On 6/28/2007 - Archived On 8/15/2007

Yee-Hsee Defends

Yee-Hsee Hsieh successfully defended his disertation "BRAINSTEM GABAA RECEPTOR SHAPES THE RESPONSE AND ADAPTATION TO HYPOXIA."  Congrats Yee-Hsee!


Posted On 6/28/2007 - Archived On 8/15/2007

Dr. Jodi is an Ironman!

   Jodi Thomson, a student in the Medical Scientist Training Program and recent graduate of the Department of Pharmacology, competed in the Ironman Challenge  in Coeur d'Alene, Idaho. As part of the challenge, Thomson was raising money for lymphoma. Read more about the race.  Judi finished in 12:27.  Good job, Jodi!
Posted On 6/22/2007 - Archived On 8/15/2007

Park Received Pathway to Independence Award

Congratulations to Paul Park who has received an NIH Pathway to Independence Award for his research proposal entitled,  "Towards a structural and temporal understanding of phototransduction". Read  more...


Posted On 6/6/2007 - Archived On 7/6/2007

Pharmacology Graduate Students Win Big!


Congratulations to Pharmacology graduate students Payal Gandhi, Yan Qu and Yiping Rong who all won Poster Presentation Awards at this years Biomedical Graduate Student Symposium!


Posted On 5/23/2007 - Archived On 6/22/2007

The Yin and Yang of Retinoic Acid Signalling

Noa Noy and her lab published their recent work on how retinoic acid affects cell growth by activating two different nuclear receptors. Read more...
 
 


Posted On 5/22/2007 - Archived On 6/21/2007

A Successful Defense!


Jodi Thomson
delivered her final dissertation, entitled "Overcoming Inhibitor Resistance in the SHV Beta-Lactamase" on Friday, May 18th. Jodi is an MSTP student who worked in Dr. Robert Bonomo's lab. Great job, Jodi!


Posted On 5/21/2007 - Archived On 6/20/2007

Good News!


Yan Qu won the "Graduate Student Best Abstract Award" of the American Society for Pharmacology and Experimental Therapeutics (ASPET) in Experimental Biology 2007 conference held in Washington DC from Apr. 28 to May 3, 2007. Good Job, Yan!


Posted On 5/8/2007 - Archived On 6/7/2007

2007 A.L. Chilton Lecture

chilton


Krzysztof Palczewski, Ph.D., John H. Hord Professor and Chair was the 2007 A.L. Chilton Lecturer in the Department of Biochemistry at UT Southwestern Medical Center. Dr. Palczewski is pictured in the company of Nobel laureates Drs. Johann Deisenhofer, Michael Brown, Josepha Goldstein and Alfred Gilman (left to right).


Posted On 5/7/2007 - Archived On 6/6/2007

Scientific Research Symposium

symposium

Sponsored by
Interim Dean, Pamela B. Davis, M.D., Ph.D.
and the Department of Pharmacology
Friday, May 11, 2007
9:00am-5:00pm
Wolstein Auditorium
2103 Cornell Road
Download the Symposium Program

Links for the live webcast for Friday talks


Posted On 5/7/2007 - Archived On 5/11/2007

Research Showcase Award Winners!

Congratulations to pharmacology graduate student, Yiping Rong (1st place - Interaction of Bc1 - 2 with the Activation Coupling Domain of IP3 Receptor) and Tim Miller (honorable mention - FXYD5 is upregulated) in cystic fibrosis airway epithelia and modulates wound healing) for their award winning poster presentations at the 2007 Research ShowCASE.


Posted On 5/4/2007 - Archived On 5/11/2007

Off to LA!

Rod Nibbe and Jonathan Mosley both had abstracts accepted by the American Association for Cancer Research (AACR). They will be presenting their work at the annual conference in Los Angeles this April. Great Job, Rod and Jonathan!
Posted On 3/16/2007 - Archived On 4/15/2007

Congratulations to recent student JBC authors

Melissa Shelton of the Mieyal laboratory is publishing her work entitled, “Glutaredoxin regulates nuclear factor kappa-B and intercellular adhesion molecule in Muller cells: Model of diabetic retinopathy” in the Journal of Biological Chemisty.

Tara Ellison of the MacDonald laboratory is publishing her work entitled, “Evidence for 1,25(OH)2D3-independent transactivation by VDR: Uncoupling the receptor and ligand in Keratinocytes” in the Journal of Biological Chemistry.


Posted On 3/13/2007 - Archived On 5/12/2007

Gallogly Receives NRSA Grant:

Congratulations to Molly Gallogly of the Mieyal laboratory who has received an NRSA F30 pre-doctoral grant for MD/PhD students for her work on the "Role of GRx in the regulation of calcium homeostasis in the aging heart."
Posted On 3/13/2007 - Archived On 5/12/2007

Graduate Student Efforts Feed the Hungry:

Appreciation goes out to the graduate students of the Department of Pharmacology who collected 108 food items and $164 during the CWRU Graduate Student Senate (GSS) annual Food Drive. This is the third consecutive year that the Department of Pharmacology has earned the distinction of being the most generous during this annual event and has been honored with a financial prize from the GSS. At the suggestion of the students, the department fully supported the additional donation of this prize to the Cleveland Food Bank. The Cleveland Food Bank is one of the largest charities in Northern Ohio and potentially the largest metropolitan foodbank in the country. The Cleveland Foodbank supplies food for use in local soup kitchens, shelters and food pantries, child-care centers, group homes and programs for the elderly. For every $1 donation, the Foodbank is able to distribute enough food to prepare four nutritious meals for the hungry in the Cleveland area. The financial contributions received from the Department of Pharmacology alone will supply over 1800 meals.
Posted On 3/7/2007 - Archived On 5/7/2007

Annual Scholarship in Teaching Award:

Amy Wilson-Delfosse was awarded a 2006 Scholarship in Teaching Award that recognizes medical school faculty for making distinct contributions to education and having an impact on the advancement of medical instruction. The title of the project recognized was "Progressive Assessment in the Fundamentals of Therapeutic Agents Committee".
Posted On 1/3/2007 - Archived On 3/2/2007

Congratulations!

Nicole White successfully defended her disertation entitled "Inherent flaw of cholesterol processing in cultured and in vivo models of cystic fibrosis" on November 16th.
Posted On 1/3/2007 - Archived On 3/2/2007

PNAS

Congratulations to David Lodowski, Ph.D of the Palczewski lab upon the publication of his recent work "Structure of the Photoactivated State of Rhodopsin" in PNAS.


Posted On 12/6/2006 - Archived On 3/8/2007

Montano Honored by Ohio Cancer Research Associates:

Congratulations to Dr. Monica Montano who was recently recognized by the Ohio Cancer Research Associates for her achievements in the field of cancer research. Dr. Montano's research focuses on estrogen receptor-selective coactivators in breast cancer cells.
Posted On 11/27/2006 - Archived On 1/31/2007

Keri Makes Front Page!

Don't miss the November 27th edition of the Cleveland Plain Dealer to read about Dr. Ruth Keri's research, lab and life in science.
Posted On 11/27/2006 - Archived On 2/21/2007

Nathan S. Greenfield Family Lecture

Dr. Robert J. Lefkowitz



The Department of Pharmacology welcomed Dr. Robert J. Lefkowitz for the annual Nathan S. Greenfield Family Lecture. View Dr. Lefkowitz's seminar "Seven Transmembrane Receptors".


Posted On 10/25/2006 - Archived On 12/25/2006

Kiser Receives Loan Repayment Award:

Congratulations to Philip Kiser who received an award from the Pediatric Loan Repayment Program administered through the NIH.
Posted On 10/24/2006 - Archived On 11/23/2006

Young Scientist Award:

Congratulations to Yan Qu who won the 1st place award in the Van Arman Young Scientist Award Competition at the 14th international meeting of the Inflammatory Research Association held in Cambridge, Maryland.
Posted On 10/20/2006 - Archived On 11/19/2006

Retreat 2006 - Keynote Speaker

Anthony Adamis

The Department of Pharmacology welcomed Dr. Tony Adamis ((osi) eyetech) as our keynote speaker for the 2006 Departmental Research Symposium held at Squire Vallevue Farm.
Posted On 10/19/2006 - Archived On 11/16/2006

Wilson-Delfosse Wins Medical Education Award:

Congratulations to Amy Wilson-Delfosse for winning the Outstanding Presentation Award at the 2006 meeting of the International Association of Medical Science Educators (IAMSE) for her work entitled, "Team-based Learning: An Effective Method for Teaching Pharmacology". Amy's was one of approximately 90 presentations given at the annual meeting.
Posted On 10/17/2006 - Archived On 12/1/2006

Retreat 2006 Awards!

Vivian Gama

Congratulations to Vivian Gama who received the Student of the Year award. Elizabeth Sabens received the Greenfield Travel Award and Payal Gandhi received the best Retreat Presentation Award sponsored by Lerner Research Institute.



Posted On 10/11/2006 - Archived On 11/12/2006

Renovations Begin!

palczewski

The Chair of the Department of Pharmacology, Kris Palczewski, Vice Chair John Mieyal, and Michael Maguire, the architectural liaison for the Department, in the official wall breaking, all of whom enthusiastically wielded a sledgehammer to begin the demolition of the current third floor laboratories, marking the exciting beginning of the first phase of construction of completely new laboratories for the Department. Read More about the renovations
Posted On 8/15/2006 - Archived On 10/25/2006

Noa Noy Joins Department of Pharmacology

RABP-I

Dr.Noa Noy, well-known nuclear receptor expert, is joining the Case faculty as professor in the Department of Pharmacology. Read full story...



Posted On 6/13/2006 - Archived On 10/1/2006

Registration now open

The Department of Pharmacology Retreat registration and abstract submission is now open! Click here for information and registration.

 The registration and abstract submission closes on October 6th.


Posted On 9/2/2008 - Archived On 10/6/2008

The Department of Pharmacology (Case School of Medicine) in collaboration with the Department of Psychiatry (University Hospitals of Cleveland) seeks to identify a faculty member(s) to direct the development of a highly collaborative program of Neuropharmacology within the Department of Pharmacology. More details and application instructions are available here.
Posted On 4/1/2006 - Archived On 4/30/2006

Keri Scores!

Congratulations to Ruth Keri for her 6.6 percentile score on her NCI competitive renewal “Regulation of erbB2/Neu-induced mammary gland cancer”!
Posted On 10/17/2006 - Archived On 10/25/2006

Maguire receives RO1:

Mike Maguire has received a new 4 year R01 from NIGMS for his project entitled "Magnesium Homeostasis in Microorganisms". The Maguire lab has also been very prolific over the last couple months. Click here for a list of their most recent publications.
Posted On 7/25/2006 - Archived On 8/24/2006

Keri Receives Komen Award:

Ruth Keri has received a Susan G. Komen Breast Cancer Foundation Grant for $250,000 over two years for her proposal titled "Evaluating the role of GKLF/KLF4 in mammary gland development and carcinogenesis". Click here to learn more about the Komen Foundation and its goal to eradicate breast cancer.
Posted On 7/24/2006 - Archived On 8/23/2006

Chen and Wilson-Delfosse Receive NPF Mega Award:

Congratulations to Shu Chen and Amy Wilson-Delfosse whose collaborative proposal entitled “Uncovering the pathogenic role of LRRK2 in Parkinson disease using molecular and chemical genetic approaches” has received a National Parkinson Foundation Mega Award.
Posted On 7/24/2006 - Archived On 8/23/2006

Keri in the News:

Orange Country Register Reporter, Gary Robbins (aka Sciencedude) interviews Ruth Keri on genes and breast cancer. Hear the audio blog.
Posted On 5/30/2006 - Archived On 6/30/2006

Maquire

Congratulations to Dr. Michael Maguireon the publication of the crystal structure of CorA Mg2+ channel in the April 6 edition of Nature.
Read more


Posted On 4/13/2006 - Archived On 6/2/2006

Congratulations

to Tara Ellison, Nicole White and Jonathan Mosley for being selected to present their research at the NIH National Graduate Student Research Festival held this October at the NIH. All expenses are paid, and up to 250 students are involved.
Posted On 8/28/2006 - Archived On 9/27/2006

At the Gordon Research Conference, "Drug Carriers in Medicine and Biology", the Chair's award for the best student poster presentation was presented to graduate student, Jose Gomez. Good job, Jose!
Posted On 8/28/2006 - Archived On 9/27/2006

Congratulations to Gina Bernardo who successfully competed for a Pre-doctoral fellowship from the Department of Defense Breast Cancer Research Program with her proposal entitled "Functional interaction between Her2/ErbB2 and Met receptor signaling in breast cancer." Gina is completing her thesis work in the Keri laboratory. For more information on the DODBCRP please follow This Link .
Posted On 8/22/2006 - Archived On 9/21/2006

Yan Qu has been selected as a finalist for the 2006 C. Gordon Van Arman Scholarship Award competition. Based on a submitted paper, she will compete at the International IRA Conference in October. Good luck Yan!
Posted On 7/14/2006 - Archived On 8/13/2006

Please congratulate Krisztina Papp-Wallace. She has received a $500 travel award from the American Society for Microbiology to attend the "2nd International Conference on Salmonella" to he held in September in Victoria, British Columbia.
Posted On 7/14/2006 - Archived On 8/13/2006

Congratulations to Jodi Thomson who in one week published two articles in the June edition of JBC. Her articles can be found at Probing active site chemistry in SHV beta-lactamase variants at Ambler position 244: Understanding unique properties of inhibitor resistance and Structural and computational characterization of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein(BLIP) interface
Posted On 6/30/2006 - Archived On 7/30/2006

Prelim I Success!

Congratulations to Linnea Patt and Elizabeth Sabens who recently withstood the rigors of the two-part Prelim I examination and passed.
Posted On 6/27/2006 - Archived On 7/27/2006

Congratulations to Mike Davis who successfully defended his dissertation entitled "“Investigations into the Generation and Regulation of Pro- Apoptotic Ca²+ Signals in T Cells.”
Posted On 6/8/2006 - Archived On 7/8/2006

Congratulations go to Marjorie Montanez-Wiscovich who has received an NRSA pre-doctoral training award from the National Cancer Institute.
Posted On 6/2/2006 - Archived On 7/2/2006

Congratulations go to Jose Gomez who recently received an American Heart Association Predoctoral Fellowship with an outstanding score.
Posted On 5/10/2006 - Archived On 6/10/2006

Pharmacology Students Win Biomedical Graduate Student Symposium Competitions!

Marjorie Montanez-Wiscovich received the President's award for the best oral presentation at the Case Biomedical Graduate Student Symposium ("LMO4 is Necessary for Maintenance of Cyclin D1 Expression in Breast Cancer Cells"). Melissa Bentle ("Altered Cellular Metabolism and Repair Through Poly(ADP-ribose) Polymerase-1 Hyperactivation to Enhance Cancer Therapy") and Vivian Gama ("Poly-Glutamine Disease Induces Bax-Mediated Cell Death through Ku70 Acetylation") were recognized as winners in the poster presentation session. Congratulations to these students and all students who took part in this event.
Posted On 5/8/2006 - Archived On 5/15/2006

Congratulations to recent graduate Melissa Landis whose manuscript entitled, "Sustained trophism of the mammary gland is sufficient to accelerate and synchronize development of ErbB2/Neu-induced tumors" has been published in Oncogene. Melissa is now a post-doctoral fellow in Jeff Rosen's lab in the Molecular and Cellular Biology Department at Baylor College of Medicine. Her work focuses on identifying mammary cancer stem cells.
Posted On 5/2/2006 - Archived On 6/2/2006

Congratulations to Vivian Gama who won the University Hospitals of Cleveland Award for the presentation of her poster, "Polyglutamine disease induces Bax-mediated cell death through Ku70 acetylation" at the Research ShowCASE.
Posted On 5/2/2006 - Archived On 6/2/2006

Marjorie Montanez-Wiscovich has received a travel award from the Endocrine Society to attend their 88th annual meeting in Boston in June, 2006. The title of her oral presentation is "LMO4 is necessary for maintenance of Cyclin D1 expression in breast cancer cells".
Posted On 5/2/2006 - Archived On 6/2/2006

Congratulations go to Yu-Ting Chou who successfully defended his dissertation entitled “Cited2, an autoregulated transcriptional modulator, in TGF- b signaling” on May 3, 2006. Yu-Ting plans to start interviewing for PostDoc positions this summer.
Posted On 5/2/2006 - Archived On 6/2/2006

Congratulations go to John Poirier who won first place in the Michelson-Morley Biology Research Competition for Case Undergraduates with his presentation entitled "Rapamycin inhibits primary tumor growth in a transgenic model of HER2-dependent breast cancer." He was also awarded second place for his research paper with the same title that was submitted to the SOURCE Undergraduate Research Symposium in the category of Natural Sciences. John is completing his undergraduate research in Dr. Ruth Keri's laboratory and will join the Ph.D. training program in Cellular and Molecular Medicine at Johns Hopkins University in the fall. For more information about SOURCE, please see the following link: http://www.case.edu/provost/source/index.html.
Posted On 5/2/2006 - Archived On 6/2/2006

Graduate Student Symposium

Don't miss the 29th Annual Biomedical Graduate Student Symposium to be held on May 5, 2006. Representing the Department of Pharmacology are poster presenters: Smitha P. Sripathy, Jennifer L. Yori, Jonathan Mosley, Payal N. Gandhi, Reginald C. Gray, Vivian Gama, Tara Ellison,Melissa D. Shelton, Jose A. Gomez, Andrea S. Moomaw, Jodi M. Thomson, Melissa S. Bentle and Marjorie Montanez-Wiscovich with an oral presentation. Please see http://filer.case.edu/org/bgss/schedule.html for complete details.
Posted On 5/2/2006 - Archived On 5/6/2006

New Students:

The Department of Pharmacology would like to welcome four new students to the Molecular Therapeutics Training Program from the Biomedical Sciences Training Program . Reema Wahdon and Jennifer Leising will be joining Dr. Danielpour's lab, Gina Bernardo will be joining Dr. Keri's lab, and Xiaoming Zhou will be joining Dr. Palczewski's lab.
Posted On 4/13/2006 - Archived On 5/1/2006

Ndiya Ogba received a highly competitive Department of Defense Fellowship. Ndiya was recognized for her past two years of research on the estrogen receptor in breast cancer. This is a three year fellowship that will support her continued work in this area of research.
Posted On 4/13/2006 - Archived On 5/1/2006

Jodi Thomson received a travel fellowship from the American Society for Biochemistry and Molecular Biology (ASBMB) to attend the 2006 Experimental Biology conference in San Francisco April 1-5.
Posted On 4/13/2006 - Archived On 5/1/2006

Philip Kiser was recently appointed to the Visual Sciences Training Grant. This is a T32 training grant awarded to Case from the Department of Health and Human Services. Awards are appointed based on a competitive application process to students doing vision-related dissertation research.
Posted On 4/13/2006 - Archived On 5/1/2006

Congratulations toVivien Gama whose publication "Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis" appears in the February 15 edition of Experimental Cell Research (Gama V, Yoshida T, Gomez JA, Basile DP, Mayo LD, Haas AL, Matsuyama S.; Exp Cell Res. 2006 Feb 15;312(4):488-99).
Posted On 4/13/2006 - Archived On 5/1/2006

Congratulations to recent graduate Melissa Landis whose manuscript entitled, "Sustained trophism of the mammary gland is sufficient to accelerate and synchronize development of ErbB2/Neu-induced tumors" has been published in Oncogene. Melissa is now a post-doctoral fellow in Jeff Rosen's lab in the Molecular and Cellular Biology Department at Baylor College of Medicine. Her work focuses on identifying mammary cancer stem cells.
Posted On 4/13/2006 - Archived On 5/1/2006

Please congratulate Krisztina Papp-Wallace. Her review for Volume 60 of Annual Reviews of Microbiology 2006, "Manganese Transport and the Role of Manganese in Virulence", has been accepted by the reviewers and editors with NO recommended revisions.
Posted On 4/13/2006 - Archived On 6/1/2006

The Department of Pharmacology would like to congratulate Samantha Cicero on successfully defending her dissertation entitled "The Roles of Cdk5 in Neuronal Development and Neurodegeneration". Samantha will continue her research by investigating the role of retinoblastoma (Rb) in cell cycle exit and neuronal differentiation as a Post-Doctoral Fellow in Dr. Michael Dyer's laboratory at St. Jude Children's Research Hospital.
Posted On 3/13/2006 - Archived On 5/1/2006

Congratulations to Paul Park who has received a three year postdoctoral fellowship from The Foundation Fighting Blindness!
Posted On 5/18/2006 - Archived On 6/16/2006

Congratulations to Emhonta (Monty) Johnson who was appointed to the Oncological Sciences Training Grant.


Posted On 4/13/2006 - Archived On 6/2/2006

Department of Pharmacology Alumni, click here to take our Alumni Survey.
Posted On 5/2/2006 - Archived On 7/31/2006